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SkinMedica TNS Advanced+ Serum

  • SkinMedica's #1 best-seller
  • Anti-aging, multi-tasking serum
  • Plumps and smooths
$295.00

1 oz


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Same Day, Next Day Shipping - Mon-Fri

  • Age-Refying Results

    Rejuvenates skin

  • Peptide Power

    Firms and lifts sagging skin

  • Smooths Wrinkles

    And fine lines

  • Instant Hydration

    Long-term too!

Details

TNS Advanced: Growth Factor Power: Boosts Natural Renewal

SkinMedica TNS Advanced+ Serum is a next-level growth factor treatment clinically proven to reduce the appearance of fine lines and deep wrinkles in as little as 2 weeks. This dual-chamber serum delivers two powerhouse formulas: one packed with growth factors to support skin renewal and another with a blend of botanicals and peptides to lift, firm, and smooth.

SkinMedica new and improved packaging and pump! Same incredible product, more effective product delivery.

Clinical Highlights:

  • Visible reduction in coarse wrinkles in just 2 weeks.
  • Continued improvement in skin tone and texture over 24 weeks.
  • 100% of patients in a clinical study showed smoother, younger-looking skin.
  • Look Up to 6 Years Younger: In a third-party validated study, participants reported looking as much as six years younger after 12 weeks.
  • Lift and Firm: Noticeable improvements in the appearance of sagging skin were seen after 8 weeks.
  • Continued Progress: Satisfaction and visible skin improvements increased steadily through 24 weeks of ongoing use.
  • Tested with GLP-1 Patients: Clinically proven to address sagging skin.

Why You’ll Love It:

  • Fast-acting formula for noticeable results.
  • Supports healthy collagen and elastin for firmer skin.
  • Lightweight, fragrance-free texture perfect for daily use.
  • Over 1 million bottles sold. SkinMedica's #1 best-selling product!

Who It’s For:

  • Ideal for all skin types seeking advanced anti-aging results, including those with fine lines, deep wrinkles, and loss of firmness.

Discover dramatic, youthful results with consistent use of SkinMedica TNS Advanced+ Serum.

Benefits
  • Reduces the appearance of deep wrinkles
  • Improves firmness and elasticity
  • Enhances skin tone and texture
  • Hydrates and plumps for a radiant glow
  • Provides long-lasting anti-aging support

Experience powerful, visible skin renewal with every application.

How to Use

Apply a single pump morning and evening to cleansed face, neck, and décolletage. Allow the serum to absorb fully before applying moisturizer or sunscreen.

Consistency is key; use twice daily for optimal anti-aging results.

Pump tips: Prior to use, invert and tap the top of the container several times in the palm of hand.

Ingredients

Featured Ingredients:

  • TNS®-MR: A next-generation growth factor blend that supports skin regeneration and smooths fine lines.
  • Renessensce (RSC) Advanced: Botanical extracts and peptides that tighten, firm, and improve skin texture.
  • Peptides & Antioxidants: Defend against environmental stressors and support collagen production.
  • Marine Extracts: Provide deep hydration and nourishment.
  • Green Microalgae: Supports collagen and elastin levels

Scientifically formulated and dermatologist-tested for trusted, proven results.

Aqua/Water/Eau, Pentylene Glycol, Human Fibroblast Conditioned Media, Glycereth-7 Triacetate, Shea Butter Ethyl Esters, Glycerin, Ethoxydiglycol, Lactococcus Ferment Lysate, Whey Protein, Chlorella Vulgaris Extract, Saccharide Isomerate, Dimer Tripeptide-43, Vitis Vinifera (Grape) Flower Cell Extract, Pyrus Malus (Apple) Fruit Extract, Hydroxyacetophenone, Tocopheryl Acetate, Propanediol, Xanthan Gum, Polyacrylate Crosspolymer-6, Polyacrylate-13, Polyisobutene, Sclerotium Gum, PEG-12 Dimethicone, Lecithin, Pullulan, Butylene Glycol, Sodium Citrate, Polysorbate 20, Aminomethyl Propanol, Disodium EDTA, Phenoxyethanol, Ethylhexylglycerin.

Ingredients may change. Please check the packaging for the most current list.

FAQ

What Are Growth Factors and How Do They Work?
Growth factors are naturally occurring proteins that support skin repair, regeneration, and overall health; not to be confused with growth hormones. They play a key role in skin rejuvenation by helping to repair damaged tissue, promote firmness and elasticity, and maintain the skin’s protective barrier. As we age, the skin produces fewer growth factors, and environmental stressors like UV rays and pollution can break down those that remain. The advanced growth factors in SkinMedica TNS Advanced+ Serum help rejuvenate and strengthen the skin, improve tone and texture, soften fine lines and wrinkles, and provide lasting hydration and brightness.

Who Can Use TNS Advanced+ Serum?
This serum is suitable for all skin types. It targets visible signs of aging in mature skin while helping younger skin delay the appearance of fine lines and loss of firmness.

How to Apply TNS Advanced+ Serum
Use morning and night after cleansing and toning. Press the center of the pump to dispense one pump onto the back of your hand, blend the dual formulas together, and apply evenly to your face, avoiding the eye area.

How soon will I see results?
Many users notice improved smoothness and reduced wrinkles in as little as 2 weeks, with continued improvement over 24 weeks. Results vary per person.

Can I use this with retinol or other active treatments?
Yes, TNS Advanced layers well with retinol and other actives. Apply it before heavier creams or oils. Appy it before HA5 Hydra Collagen Hydrator.

Is it safe for sensitive skin?
This fragrance-free, non-comedogenic formula is suitable for most skin types, including sensitive skin.

Can I use it under makeup?
Absolutely. Its lightweight texture absorbs quickly and works well under makeup.

How long does one bottle last?
With typical application, twice-daily use, one 1 oz bottle typically lasts about 6–8 weeks.

Experience a breakthrough in anti-aging science with TNS Advanced+ Serum and find out for yourself why this is SkinMedica's #1 product!

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Frequently Asked Questions

Shipping

How much does shipping cost?

Free Shipping

Free standard shipping is available on domestic orders that meet the minimum product total shown in the site banner ($75). Shipping fees are not included in the qualifying amount.

Shipping Rates

  • USPS Ground Advantage - $10
  • UPS - Calculated at Checkout

Shipping Extras

  • Signature Confirmation available for $3.00

Do you ship on the same day?

Fast Shipping

We ship Monday to Friday, from our spa in Florida.

Same Day Shipping Deadlines

  • Monday to Friday - Order by 2 pm PST
  • Saturday, Sunday, Holidays - No Shipping

What countries do you ship to?

We currently ship to the United States.

Details

TNS Advanced: Growth Factor Power: Boosts Natural Renewal

SkinMedica TNS Advanced+ Serum is a next-level growth factor treatment clinically proven to reduce the appearance of fine lines and deep wrinkles in as little as 2 weeks. This dual-chamber serum delivers two powerhouse formulas: one packed with growth factors to support skin renewal and another with a blend of botanicals and peptides to lift, firm, and smooth.

SkinMedica new and improved packaging and pump! Same incredible product, more effective product delivery.

Clinical Highlights:

  • Visible reduction in coarse wrinkles in just 2 weeks.
  • Continued improvement in skin tone and texture over 24 weeks.
  • 100% of patients in a clinical study showed smoother, younger-looking skin.
  • Look Up to 6 Years Younger: In a third-party validated study, participants reported looking as much as six years younger after 12 weeks.
  • Lift and Firm: Noticeable improvements in the appearance of sagging skin were seen after 8 weeks.
  • Continued Progress: Satisfaction and visible skin improvements increased steadily through 24 weeks of ongoing use.
  • Tested with GLP-1 Patients: Clinically proven to address sagging skin.

Why You’ll Love It:

  • Fast-acting formula for noticeable results.
  • Supports healthy collagen and elastin for firmer skin.
  • Lightweight, fragrance-free texture perfect for daily use.
  • Over 1 million bottles sold. SkinMedica's #1 best-selling product!

Who It’s For:

  • Ideal for all skin types seeking advanced anti-aging results, including those with fine lines, deep wrinkles, and loss of firmness.

Discover dramatic, youthful results with consistent use of SkinMedica TNS Advanced+ Serum.

Benefits
  • Reduces the appearance of deep wrinkles
  • Improves firmness and elasticity
  • Enhances skin tone and texture
  • Hydrates and plumps for a radiant glow
  • Provides long-lasting anti-aging support

Experience powerful, visible skin renewal with every application.

How to Use

Apply a single pump morning and evening to cleansed face, neck, and décolletage. Allow the serum to absorb fully before applying moisturizer or sunscreen.

Consistency is key; use twice daily for optimal anti-aging results.

Pump tips: Prior to use, invert and tap the top of the container several times in the palm of hand.

Ingredients

Featured Ingredients:

  • TNS®-MR: A next-generation growth factor blend that supports skin regeneration and smooths fine lines.
  • Renessensce (RSC) Advanced: Botanical extracts and peptides that tighten, firm, and improve skin texture.
  • Peptides & Antioxidants: Defend against environmental stressors and support collagen production.
  • Marine Extracts: Provide deep hydration and nourishment.
  • Green Microalgae: Supports collagen and elastin levels

Scientifically formulated and dermatologist-tested for trusted, proven results.

Aqua/Water/Eau, Pentylene Glycol, Human Fibroblast Conditioned Media, Glycereth-7 Triacetate, Shea Butter Ethyl Esters, Glycerin, Ethoxydiglycol, Lactococcus Ferment Lysate, Whey Protein, Chlorella Vulgaris Extract, Saccharide Isomerate, Dimer Tripeptide-43, Vitis Vinifera (Grape) Flower Cell Extract, Pyrus Malus (Apple) Fruit Extract, Hydroxyacetophenone, Tocopheryl Acetate, Propanediol, Xanthan Gum, Polyacrylate Crosspolymer-6, Polyacrylate-13, Polyisobutene, Sclerotium Gum, PEG-12 Dimethicone, Lecithin, Pullulan, Butylene Glycol, Sodium Citrate, Polysorbate 20, Aminomethyl Propanol, Disodium EDTA, Phenoxyethanol, Ethylhexylglycerin.

Ingredients may change. Please check the packaging for the most current list.

FAQ

What Are Growth Factors and How Do They Work?
Growth factors are naturally occurring proteins that support skin repair, regeneration, and overall health; not to be confused with growth hormones. They play a key role in skin rejuvenation by helping to repair damaged tissue, promote firmness and elasticity, and maintain the skin’s protective barrier. As we age, the skin produces fewer growth factors, and environmental stressors like UV rays and pollution can break down those that remain. The advanced growth factors in SkinMedica TNS Advanced+ Serum help rejuvenate and strengthen the skin, improve tone and texture, soften fine lines and wrinkles, and provide lasting hydration and brightness.

Who Can Use TNS Advanced+ Serum?
This serum is suitable for all skin types. It targets visible signs of aging in mature skin while helping younger skin delay the appearance of fine lines and loss of firmness.

How to Apply TNS Advanced+ Serum
Use morning and night after cleansing and toning. Press the center of the pump to dispense one pump onto the back of your hand, blend the dual formulas together, and apply evenly to your face, avoiding the eye area.

How soon will I see results?
Many users notice improved smoothness and reduced wrinkles in as little as 2 weeks, with continued improvement over 24 weeks. Results vary per person.

Can I use this with retinol or other active treatments?
Yes, TNS Advanced layers well with retinol and other actives. Apply it before heavier creams or oils. Appy it before HA5 Hydra Collagen Hydrator.

Is it safe for sensitive skin?
This fragrance-free, non-comedogenic formula is suitable for most skin types, including sensitive skin.

Can I use it under makeup?
Absolutely. Its lightweight texture absorbs quickly and works well under makeup.

How long does one bottle last?
With typical application, twice-daily use, one 1 oz bottle typically lasts about 6–8 weeks.

Experience a breakthrough in anti-aging science with TNS Advanced+ Serum and find out for yourself why this is SkinMedica's #1 product!