SkinCeuticals HA Intensifier Multi-Glycan: Volumizing Hyaluronic Acid Serum for Visibly Plumper, Fuller-Looking Skin
SkinCeuticals HA Intensifier Multi-Glycan is a corrective hyaluronic acid serum designed to go further than surface hydration. Instead of simply adding moisture, it works with the skin's glycosaminoglycans (glycans), the naturally occurring compounds that keep skin plump, to visibly restore volume, define facial contours, and fill the look of fine lines.
SkinCeuticals built the formula around five actives: 12% Proxylane, 1.3% hyaluronic acid, a 2.0% post-biotic lactobacillus and soybean ferment, 2.0% licorice root extract, and 0.2% purple rice extract. The brand reports that it amplifies the skin's own hyaluronic acid levels by 30%, rehydrates skin for up to 24 hours, and over time renews the look of elasticity and firmness. The licorice and purple rice extracts also give the serum its signature purple tint.
SkinCeuticals states the serum is clinically tested on all skin types and tones, is paraben-free and dye-free, and is physician-tested to complement dermal filler injections. It can be part of an at-home routine after fillers, with your physician advising on timing.
Why You'll Like It
- Visibly plumps skin and boosts radiance by 10% within 15 minutes, per SkinCeuticals.
- Brand study reports fine lines visibly filled by 24% after 12 weeks.
- Supports the skin's own hyaluronic acid levels rather than only adding HA on top.
- Helps define facial contours and improve the look of facial volume.
- Silky serum that layers easily between vitamin C and sunscreen.
- Physician-tested to complement dermal filler results.
Who Is It For
- Dry, normal, oily, combination, sensitive, dehydrated, and aging skin, as recommended by SkinCeuticals.
- Anyone noticing a loss of facial volume, fullness, or definition with age.
- Patients who receive dermal fillers and want a supportive daily serum.
- People who have outgrown basic hyaluronic acid serums and want visible plumping.
For skin that looks deflated rather than simply dry, SkinCeuticals HA Intensifier Multi-Glycan offers a far more ambitious approach to hydration.
Benefits
- Visibly plumps the skin's surface and enhances radiance soon after application.
- Helps fill the look of fine lines and soften the appearance of wrinkles.
- Improves the appearance of facial volume and contour definition over time.
- Amplifies the skin's own hyaluronic acid levels, according to SkinCeuticals.
- Delivers lasting hydration that improves the look of skin texture.
- Renews the look of firmness and elasticity with consistent use.
- Complements professional dermal filler treatments.
- Paraben-free, dye-free, and TSA approved.
Plumper, smoother, more defined skin starts with a serum that supports your own hyaluronic acid.
It stands among the signature serums of the SkinCeuticals clinical skincare collection, a science-led brand that pairs high-concentration actives with published study data to help professionals and shoppers build targeted regimens.
How to Use
- Once or twice daily, dispense 4 to 6 drops into your palm and dab across the forehead, cheeks, chin, and neck.
- Blend into the skin. In the morning, apply after your SkinCeuticals vitamin C antioxidant serum and before sunscreen.
- Follow with your moisturizer to lock in hydration.
Use it morning and night for the best results, since the published 12-week data reflects twice-daily application.
Ingredients
Key Ingredients:
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12% Proxylane: Supports the skin's hyaluronic acid levels to help improve the look of firmness.
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1.3% Hyaluronic Acid: A natural humectant that delivers long-lasting hydration and improves the look of skin texture.
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2.0% Lactobacillus/Soybean Ferment Extract: A post-biotic ferment that helps increase glycosaminoglycan levels and improve the appearance of facial volume.
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2.0% Licorice Root Extract (Dipotassium Glycyrrhizate) + 0.2% Purple Rice Extract: A pairing that helps prevent the breakdown of hyaluronic acid and gives the serum its purple color.
Full Ingredients: Aqua / Water / Eau, Dimethicone, Glycerin, Alcohol Denat., Hydroxypropyl Tetrahydropyrantriol, Propylene Glycol, Polyglyceryl-4 Caprate, Dipotassium Glycyrrhizate, Lactobacillus/Soybean Ferment Extract, Polysilicone-11, Sodium Hyaluronate, Sodium Hydroxide, Tocopherol, Phenoxyethanol, Capryloyl Salicylic Acid, Octyldodecanol, Bis-Peg/Ppg-16/16 Peg/Ppg-16/16 Dimethicone, Ammonium Polyacryloyldimethyl Taurate, Peg-20 Methyl Glucose Sesquistearate, Caprylyl Glycol, Xanthan Gum, Trisodium Ethylenediamine Disuccinate, Sodium Acetylated Hyaluronate, Dextrin, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Oryza Sativa Extract / Rice Extract, Caprylic/Capric Triglyceride, Adenosine, Pentylene Glycol, Citrus Nobilis Peel Oil / Mandarin Orange Peel Oil, Limonene, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate.
Ingredients may change. Please check the packaging for the most current list.
Disclosed concentrations across every key active make this one of the most transparent hyaluronic acid formulas available.
FAQ
What are glycans, and why do they matter?
Glycans, short for glycosaminoglycans, are naturally occurring compounds in the skin's matrix that provide hydration and structural support. Hyaluronic acid is the most abundant glycan, and SkinCeuticals notes that its decline with age contributes to volume loss and wrinkling. SkinCeuticals HA Intensifier Multi-Glycan is designed to support those glycan levels.
How is SkinCeuticals HA Intensifier Multi-Glycan different from other hyaluronic acid serums?
Many HA serums contain hyaluronic acid alone, which hydrates the surface. This formula combines hyaluronic acid with Proxylane, a post-biotic ferment, and licorice root and purple rice extracts that help preserve HA in the skin's upper layers. SkinCeuticals says the result is visible plumping and contouring, not just moisture.
How does it compare with Hydrating B5 Gel?
Both are SkinCeuticals hydrators, but they work differently. SkinCeuticals Hydrating B5 Gel leads with vitamin B5 for simple oil-free moisture, while the HA Intensifier focuses on increasing the skin's own hyaluronic acid for plumpness and volume. If your main concern is visible fullness and fine lines, the HA Intensifier is the more targeted choice.
Can I use it with vitamin C or P-TIOX?
Yes. SkinCeuticals pairs it with antioxidants such as SkinCeuticals C E Ferulic with 15% L-Ascorbic Acid, applied first in the morning, to visibly improve signs of aging. The brand also recommends combining it with SkinCeuticals P-TIOX Serum, its wrinkle-modulating peptide serum, for plumpness, smoothness, and radiance.
Can I use SkinCeuticals HA Intensifier Multi-Glycan with retinol?
Yes. SkinCeuticals says pairing an HA serum with retinol can complement the anti-aging benefits of each. Apply your retinol as directed and use the serum to keep skin hydrated and comfortable.
Is it a good serum to use with dermal fillers?
SkinCeuticals describes it as physician-tested to complement dermal filler injections and suitable for an at-home routine after fillers. For a broader look at making filler results last between appointments, see our guide. Always check with your injector about when to restart your routine.
Why is the serum purple?
The color comes from the licorice root and purple rice extracts in the formula. SkinCeuticals explains that these extracts work together to help prevent the degradation of hyaluronic acid in the skin.
Is there a clinical study for SkinCeuticals HA Intensifier Multi-Glycan?
Yes. According to SkinCeuticals, a 12-week, single-center clinical study was conducted on 81 females, ages 35 to 65, Fitzpatrick skin types I to VI, with mild to moderate concerns including skin softness, firmness, elasticity, fine lines, wrinkles, smoothness, plumpness, radiance, and tone evenness. The serum was applied twice daily along with a regular cleanser, moisturizer, and sunscreen, with evaluations at baseline, post-application, and at weeks 1, 4, 8, and 12.
The results the brand publishes: immediately, skin was visibly plumped with radiance improved by 10% after 15 minutes, and skin hydration was boosted for 24H. After 12 weeks, fine lines were visibly filled by 24%, the skin's hyaluronic acid levels were amplified by 30%, and skin smoothness, softness, and plumpness improved in over 90% of subjects.
In a separate 3D volume analysis on 74 of the subjects after 12 weeks of twice-daily use, SkinCeuticals reports a .69cc and .84cc volume improvement on the left and right cheeks, respectively, which the brand describes as visible surface plumping equivalent to 1cc of hyaluronic acid. The serum is not an injectable and does not replace filler. Individual results vary.
With disclosed concentrations and detailed published data, SkinCeuticals HA Intensifier Multi-Glycan is a serum you can add to your routine with real confidence.
