HYDRINITY RetaXome Daily Retinal Hydrator
- Smooths fine lines & wrinkles
- Deeply hydrates & plumps
- Boosts collagen & elasticity
- Gentle, high-tolerability formula
HYDRINITY RetaXome Daily Retinal Hydrator - 1 fl oz is backordered and will ship as soon as it is back in stock.
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Exosome Delivery
20x deeper penetration
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Stimulates Renewal
Boosts collagen + elastin
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Hydrating Formula
Minimizes dryness & flaking
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Anti-Aging Power
Firms and lifts skin

- Details
- Benefits
- How to Use
- Ingredients
- FAQ
RetaXome: Exosome-Driven Retinal Power, Reinvented for Deeper Results.
Regenerative retinoid therapy meets next-generation hydration. Hydrinity RetaXome™ Daily Retinal Hydrator is a groundbreaking anti-aging serum that fuses encapsulated retinaldehyde with biomimetic exosome delivery, proprietary peptides, and supercharged hydration technology. Designed to repair, restore, and rejuvenate, it offers faster results with higher tolerability than traditional retinoids, making it ideal for even sensitive skin.
RetaXome Daily Retinal Hydrator is a next-generation retinal serum powered by exosome technology, setting a new standard in regenerative retinoid therapy with high-dose, targeted delivery deep into the dermis, right where your skin needs it most.
Clinical Highlights
- 44% increase in skin hydration after just two weeks of use.
- No acclimation period required – consistent nightly use from day one.
- High tolerability – retinal therapy reimagined for sensitive skin.
Why You’ll Love It
- Accelerated results with less irritation – Retinaldehyde, the direct precursor to retinoic acid, works faster than retinol while exosome encapsulation minimizes sensitivity.
- Deep, lasting hydration – Dual-weight injectable-grade hyaluronic acid plumps fine lines and strengthens the skin barrier.
- Visible age-defying benefits – Smooths wrinkles, improves firmness, and boosts elasticity by stimulating collagen and elastin.
- Skin-brightening radiance – Botanical antioxidants help even tone and restore luminosity.
- Next-generation delivery – Biomimetic exosome technology drives ingredients up to 20x deeper than free-form retinal for transformative results.
Who It’s For
All skin types, especially those concerned with:
- Fine lines and wrinkles
- Loss of firmness and elasticity
- Dull, uneven skin tone
- Dehydration or compromised barrier
- Retinoid sensitivity
With its advanced delivery system and clinically proven results, Hydrinity RetaXome Daily Retinal Hydrator is the future of retinoid therapy, designed to transform your skin with precision, power, and care.
Benefits of Hydrinity RetaXome Daily Retinal Hydrator
- Visibly reduces fine lines and wrinkles for smoother, younger-looking skin
- Boosts collagen and elastin to restore firmness and elasticity
- Improves radiance and evens skin tone for a brighter complexion
- Provides deep, long-lasting hydration with dual-weight hyaluronic acid
- Delivers up to 20x deeper penetration with exosome encapsulation technology
- Minimizes irritation; suitable for sensitive skin and consistent nightly use
- Protects against environmental stressors with powerful antioxidants and botanicals
- Helps strengthen the skin barrier and reduce inflammation
RetaXome Daily Retinal Hydrator is the smarter way to retinoid: deeper delivery, faster results, gentler feel.
Apply 2 pumps to clean face and neck morning and evening. Gently massage until fully absorbed. Follow with your favorite moisturizer or SPF in the daytime.
Consistency is key; make RetaXome part of your daily ritual for lasting results.
Pro Tips:
- Prep your skin with Hydrinity Hyacyn Active Purifying Mist
- Layer with Hydrinity Renewing HA Serum for added moisture and barrier support
- Target fine lines around the eyes with Hydrinity Eye Renew Serum
Key Technologies & Ingredients
- Encapsulated Retinal (Retinaldehyde - A potent retinoid that delivers clinically validated results without the irritation of traditional Vitamin A. With biomimetic exosome encapsulation, it penetrates deeper into the dermis, accelerating cell turnover and supporting collagen synthesis.
- Supercharged Hyaluronic Acid - A patented dual-weight, 100% injectable-grade HA that floods skin with hydration, instantly plumps fine lines, and reinforces the skin’s protective barrier.
- Sodium Retinoyl Hyaluronate - A breakthrough hybrid molecule combining the resurfacing power of a retinoid with the deep hydration of hyaluronic acid.
- Adaptogen Mushroom Complex - Rich in antioxidants to calm, protect, and rejuvenate stressed skin.
- Centella Asiatica - Known for accelerating repair, reducing inflammation, and strengthening the skin barrier.
- Ectoin - A naturally derived protector that enhances hydration and shields against UV and blue light damage.
Every ingredient in RetaXome is clinically selected to deliver maximum results with high tolerability.
Full Ingredients:
Water/Aqua/Eau, Pentylene Glycol, Squalane, Glycerin, Isosorbide Dicaprylate, Cetearyl Alcohol, Glyceryl Stearate, Niacinamide, Stearyl Alcohol, Centella Asiatica Callus Conditioned Media, Retinal, Hyaluronic Acid, Polyglutamic Acid, Ceramide NP, Ceramide EOP, Ceramide AP, Cholesterol, Phytosphingosine, Sodium Retinoyl Hyaluronate, Tocopheryl Acetate, Bisabolol, Beta-Sitosterol, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Hydroxymethoxyphenyl Decanone, Cordyceps Sinensis Extract, Grifola Frondosa Extract, Ganoderma Lucidum (Mushroom) Extract, Coprinus Comatus (Mushroom) Extract, Ectoin, Dimethicone, Caprylic/Capric Triglyceride, Phosphatidylcholine, Mannitol, Sodium Lactate, Sodium Stearoyl Glutamate, Sodium Lauroyl Lactylate, Polyacrylate Crosspolymer-6, Xanthan Gum, Carbomer, Polyglyceryl-10 Laurate, Sodium Phytate, Citric Acid, Caprylyl Glycol, Ethylhexylglycerin, Butylene Glycol, Hexylene Glycol, Polysorbate 20, Phenoxyethanol, t-Butyl Alcohol.
Ingredients may change. Please check the packaging for the most current list.
What is RetaXome™ technology?
RetaXome is Hydrinity’s proprietary delivery system that fuses retinaldehyde (a powerful Vitamin A derivative) with biomimetic exosomes. This innovation allows retinal to penetrate up to 20x deeper into the skin compared to traditional retinoids, while reducing irritation and increasing effectiveness.
How does RetaXome improve retinal delivery?
The biomimetic exosomes act like protective carriers, stabilizing the retinal and transporting it directly into the dermis. This precise, targeted delivery means faster results, enhanced collagen stimulation, and improved tolerability, without the peeling and dryness often associated with retinoids.
What makes Hydrinity RetaXome different from retinol?
Unlike retinol, which requires multiple conversions before becoming active, RetaXome uses encapsulated retinaldehyde, the direct precursor to retinoic acid. This means it works faster, penetrates deeper, and delivers results with less irritation.
Can I use Hydrinity RetaXome Daily Retinal Hydrator if I have sensitive skin?
Yes. Thanks to biomimetic exosome encapsulation, retinaldehyde is delivered gradually and precisely, making it more tolerable for sensitive skin. Many users experience minimal to no irritation, even from the first use.
How soon will I see results with this Retinal Serum?
Clinical studies show improvements in hydration and skin smoothness in as little as two weeks. With consistent daily use, most users notice enhanced radiance, reduced fine lines, and firmer skin within 4–6 weeks. Keep in mind that results vary.
Can I use this serum with other skincare products?
Absolutely. RetaXome Daily Retinal Hydrator can be layered under moisturizers, serums, and SPF. For best results, avoid combining it with other strong retinoids, and consult with your skincare professional for a personalized routine.
Do I need to gradually introduce this retinal serum?
No acclimation period is required. Thanks to its high tolerability, you can use RetaXome nightly from day one. However, if you are new to retinoids, you may choose to start every other night and build up based on comfort.
Is Hydrinity RetaXome suitable for all skin types?
Yes. This serum is designed for all skin types, including dry, sensitive, and mature skin. Its hydrating dual-weight hyaluronic acid and soothing botanicals make it both effective and gentle.
Hydrinity RetaXome™ Daily Retinal Hydrator delivers next-generation retinal therapy with deep hydration, visibly reducing wrinkles and boosting skin firmness, gentle enough for sensitive skin.
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Free standard shipping is available on domestic orders that meet the minimum product total shown in the site banner ($75). Shipping fees are not included in the qualifying amount.
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We currently ship to the United States.